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Cavisept 3%

11,50 лв.

Cavisept 3% is a hypertonic solution of NaCl
The anatomical and physiological features of the respiratory system of children aged 0–6 years is characterized by an increased viscosity of the secretion, which is why the mucous membrane of the tracheo-bronchial tree in this age group needs increased moisture.

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Description

Types of NaCl concentrations 0.9% NaCI is an “isotonic” saline solution that has no osmotic effects to help induce phlegm. The hypertonic saline of NaCI – Cavisept 3%
NaCI has an osmotic effect.
How it works?
• Restores the function of the cilia of the airway epithelium• Immunomodulatory effect
• Anti-inflammatory action
• Improves the penetration of antibiotics
• Provides drainage of the bronchial tree

EFFECTS
• Natural mucolytic effect
• Acts in the outbreak of the inflammatory process, providing a physiological counter-effect on the mechanism of osmosis
• The effect occurs immediately during inhalation
• Has additional antibacterial and immunodulating effect
• Safe for children (0+), pregnant, breastfeeding women and adults• Contains no preservatives!

• Clinical trials for 3%
• Zhang L. et.al. Nebulized hypertonic saline solution for acute bronchiolitis in infants
Cochrane Database Syst Rev. 2008 Oct 8;(4):CD006458
• Mandelberg et.al. Nebulized 3% Hypertonic Saline Solution Treatment in Hospitalized Infants With Viral Bronchiolitis
Chest 2003;123;481-487
• Sarrell EM et.al. Nebulized 3% hypertonic saline solution treatment in ambulatory children with viral bronchiolitis decreases symptoms
Chest, 2002 Dec; 122(6):2015-20
• Sauvaget E. et.al. Nebulized hypertonic saline and acute viral bronchiolitis in infants: current aspects
Arch Pediatr 2012 Jun;19(6):635-41. Epub 2012 Apr 30
• Nagakumar P. et.al. Current therapy for bronchiolitis
Arch Dis Child 2012 Sep;97(9): 827-30. Doi: 10.1136/archdischild-2011-301579. Epub 2012 Jun 25
• Grewal S et.al. A randomized trial of nebulized 3% hypertonic saline with epinephrine in the treatment of acute bronchiolitis in the emergency department
Arch Pediatr Adolesc Med 2009 Nov; 163(11):1007-12. Doi: 10.1001/archpediatrics.2009.196.
• Tal G et.al. Hypertonic saline/epinephrine treatment in hospitalized infants with viral bronchiolitis reduces hospitalization stay: 2 years experience
Isr Med Assoc J. 2006 Mar;8

Cavisept 3% nacl may be useful for:
– Acute upper respiratory tract infections: rhinitis, rhinopharyngitis, laryngitis-acute infections in the lower respiratory tract: tracheitis, bronchiolitis, bronchopneumonia-allergic diseases of the respiratory system: allergic rhinitis and bronchial asthma-chronic diseases of the respiratory tract: bronchiectasis, cystic fibrosis, chronic obstructive pulmonary disease-immunoprophylaxis and immunomodulation of upper and lower respiratory tract pathology.
Hypertrophy of the adenoids surgety
after interventions of the nose and paranasal cavities.
– Daily nasal hygiene, especially in cases of drying of the nasal mucosa.

Method of administration
For single use only.
Use for 0+ year inhalation or nasal lavage after six months. 2 to 4 ml are inhaled twice daily through the nose or mouth using an inhaler and / or intranasal. If necessary, the dosage can be increased to 4 times daily.
Form and appearance
Pack of 18 vials of 4 ml single dose.
Composition
Sodium chloride: 3g; purified water (sufficient for quantity): 100 ml; without preservatives.
Directions for use: Separate the vial from the package and open it by turning the top. Pour the inhalation solution into the inhaler. Use your inhaler according to the manufacturer’s instructions supplied with the system.
MECHANISM OF ACTION
• Restores function
• Immunomodulatory effect
• Anti-inflammatory action
• Improves the use of antibiotics
• Provides drainage of the bronchial tree
• Bronchial mucosa
EFFECTS
• Natural mucolytic effect
• Acts in the outbreak of the inflammatory process, providing a physiological counter-effect on the mechanism of osmosis
• The effect occurs immediately during inhalation
• Has additional antibacterial and immunodulating effect
• Safe for children (0+), pregnant, breastfeeding women and adults• Contains no preservatives!
Clinical trials for 3% solution
• Zhang L. et.al. Nebulized hypertonic saline solution for acute bronchiolitis in infants
Cochrane Database Syst Rev. 2008 Oct 8;(4):CD006458
• Mandelberg et.al. Nebulized 3% Hypertonic Saline Solution Treatment in Hospitalized Infants With Viral Bronchiolitis

Chest 2003;123;481-487
• Sarrell EM et.al. Nebulized 3% hypertonic saline solution treatment in ambulatory children with viral bronchiolitis decreases symptoms

Chest, 2002 Dec; 122(6):2015-20
• Sauvaget E. et.al. Nebulized hypertonic saline and acute viral bronchiolitis in infants: current aspects

Arch Pediatr 2012 Jun;19(6):635-41. Epub 2012 Apr 30
• Nagakumar P. et.al. Current therapy for bronchiolitis

Arch Dis Child 2012 Sep;97(9): 827-30. Doi: 10.1136/archdischild-2011-301579. Epub 2012 Jun 25
• Grewal S et.al. A randomized trial of nebulized 3% hypertonic saline with epinephrine in the treatment of acute bronchiolitis in the emergency department

Arch Pediatr Adolesc Med 2009 Nov; 163(11):1007-12. Doi: 10.1001/archpediatrics.2009.196.
• Tal G et.al. Hypertonic saline/epinephrine treatment in hospitalized infants with viral bronchiolitis reduces hospitalization stay: 2 years experience

Isr Med Assoc J. 2006 Mar;8
Method of administration
It is inhaled twice daily with 2 to 4 ml of the solution through the nose or mouth using an inhaler and / or intranasal. If necessary, the dosage can be increased to 4 times per daily.
Form and appearance
Pack of 18 vials of 4 ml single dose.
Composition
Sodium chloride: 3d; Purified water (sufficient for quantity): 100 ml; Preservative-free Instructions for use: Separate the vial from the package and open it by turning the top. Pour the inhalation solution into the inhaler. Use your inhaler according to the manufacturer’s instructions supplied with the system.

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